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KMID : 0363220080460101445
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Korean Journal of Dermatology
2008 Volume.46 No. 10 p.1445 ~ p.1448
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A Case of Dystrophic Calcinosis Cutis Secondary to Localized Scleroderma
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Park Hwa-Young
Choi Eung-Ho
Ahn Sung-Ku
Kim Jae-Hong
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Abstract
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Localized scleroderma is a connective tissue disorder that’s characterized by thickening and fibrosis of the skin due
to excessive collagen deposition. Localized scleroderma differs from systemic sclerosis according to the absence of
Raynaud’s phenomenon, sclerodactyly or systemic involvement. Dystrophic calcinosis cutis occurs in up to 10% of
the patients with systemic sclerosis, but it is rare in localized scleroderma. Only seven cases of localized
scleroderma with calcinosis cutis have been reported in the English medical literature. We report here on a
57-year-old woman with localized scleroderma with dystrophic calcification, and this was identified by the
histopathology and CT scans. The serologic tests for the autoimmune antibodies anti-RNP, ENA and anti-SS-A(Ro)
were all positive.
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KEYWORD
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Anti-RNP antibody, Dystrophic calcinosis cutis, Localized scleroderma
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